Catalog

Genotyping is the identification of small differences in DNA that can lead to a change in phenotype, including physiological or pathological changes. Genotyping is widely used in basic research, medicine and agriculture and allows you to determine differences in DNA by comparing the sequence in the sample under study with another sequence or reference sequence. Types of genetic variation include single nucleotide variants (SNV), single nucleotide polymorphisms (SNP), insertions and deletions (indels), and copy number variations (CNV). SNP are single nucleotide changes in DNA that regularly occur in the genome. There are over 660 million known SNP in the human genome, making them the most common type of genetic variation in humans. Some SNPs are closely associated with human diseases or can act as markers that indicate the risk of developing a disease. Also, genotyping contributes to the selection of new strains of animals and plants for the choice of genotype, phylogenetic relationships between species, or verification of family ties by inheritance. Major genotyping approaches include DNA sequencing, mass spectrometry, molecular beacons, SNP microarrays, and PCR-based methods. We offer custom, primers and probes and intercalating-dye based options for the development the assay based on your research.

Highaffinity oligonucleotides