- Life Science
- In vitro diagnostics
- Synthesis of oligonucleotides
- Primers
- Fluorescently labeled probes and samples
- Oligonucleotides GentaOligoPure
- Modifications
- ‘Click’ chemistry modifications
- 2'-F (2'-Fluoro) RNA modification
- Phosphorothioate bonds
- 2'-MOE (2'-O-Methoxyethyl) RNA modification
- 2'-OMe (2'-O-Methyl) RNA modification
- LNA (Locked Nucleic Acid) RNA modification
- Other modifications
- Phosphorylation
- Thiophosphate bonds
- Fluorophores and quenchers
- Linkers and functionalization
- Reagents for molecular biology
- Services
‘Click’ chemistry modifications
Click chemistry is a versatile technique for the synthesis of a variety of biomolecules conjugates such as Nucleic Acids (DNA/RNA), peptides, proteins, and antibodies. Besides of oligonucleotide labeling, click chemistry allows the multiple labeling of polymerized DNA strands via incorporation of Alkyne-dNTPs (triphosphates) followed by post-synthetic click reactions with high efficacy.
Most popular applications:
- Fluorescence In Situ Hybridization (FISH)
- qPCR-Assays
- DNA/RNA Microarrays
- Bioconjugation to Nanoparticles
- Fluorescence Microscopy
- Electrophoretic Mobility Shift Assay (EMSA)
- Fluorescence Activated Cell Sorting (FACS)
- Flow Cytometry (FCM), Cell Tracking and Cell-based Assays
- Fluorescence Correlation Spectroscopy (FCS)
Azides
Функциональная группа терминальный азид
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