- Life Science
- In vitro diagnostics
- Synthesis of oligonucleotides
- Primers
- Fluorescently labeled probes and samples
- Oligonucleotides GentaOligoPure
- Modifications
- ‘Click’ chemistry modifications
- 2'-F (2'-Fluoro) RNA modification
- Phosphorothioate bonds
- 2'-MOE (2'-O-Methoxyethyl) RNA modification
- 2'-OMe (2'-O-Methyl) RNA modification
- LNA (Locked Nucleic Acid) RNA modification
- Other modifications
- Phosphorylation
- Thiophosphate bonds
- Fluorophores and quenchers
- Linkers and functionalization
- Reagents for molecular biology
- Services
Azides
Azide Modification. If you require this modification, please contact us info@genterra.ru
Terminal azide is a functional group, which can be incorporated into oligonucleotide internally or at 5’- and 3’-ends. Alkyne oligonucleotides can be conjugated with aдлнту-containing labels/tags (e.g., fluorescent dyes, biotin, or oligos) with high regioselectivity and efficiency using “Click Chemistry” (a [3+2] cycloaddition in presence of copper (I) ions or in Strain promoted “Click Chemistry”).
Available sites for modifications are 5’, internal and 3’.
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